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The Technology Behind Oral Semaglutide, and the Mechanism of Its Absorption Historically, peptides and proteins have offered efficacious treatment options either as replacements in diseases where the native peptide- or protein-based hormone is not being produced endogenously, or it is being produced or secreted in smaller amounts than required (e.g., insulin in type 1 diabetes, growth hormone in growth disorders, factor VIII in hemophilia disorders)
They will also share the same mechanism of action (GLP-1 receptor agonist) and a broadly similar side-effect profile of nausea, indigestion and stomach pain
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