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In a mouse model of pancreatic cancer liver metastasis, the use of IGF-IR inhibitor IGF-Trap reshaped the local immunosuppressive microenvironment of liver tumors, reduced the recruitment of bone marrow-derived suppressor cells, reversed innate immune cell polarization and inhibited metastatic expansion
Neurotransmitter-induced inhibition of exocytosis in insulin-secreting beta cells by activation of calcineurin
J Postgrad Med
The case for co-administration is not that they fail apart
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