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Some studies confirmed that in neurodegenerative diseases, spermidine also activates mitophagy by enhancing PINK expression, which prolongs lifespan, improves health span, protects against memory loss and increases locomotor activity (Reference Filfan, Olaru and Udristoiu78, Reference Yang, Zhang and Dai79)
This results in: Systemic muscle growth across the entire body Enhanced fat metabolism and insulin sensitivity Ideal pairing with long-acting growth agents like HGH, MK-677, and anabolic steroids Long R3 IGF-1 was engineered to increase receptor activity and reduce IGFBP interference, extending its biological availability and enhancing systemic effects. Duan, Frontiers in Endocrinology IGF-1 DES (1-3): Targeted Anabolic Precision IGF-1 DES is a truncated analog that removes the first three amino acids from the IGF-1 protein chain
10.1172/JCI76881 J
Jung J et al
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