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This method has been validated in mouse models and offers a potential tool for clinical monitoring of inflammatory status in kidney transplant recipients [125]
The drug, which stimulates GLP-1 and glucagon receptors, led to a 16.6% drop in body weight
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In sarcopenic muscle, reduced insulin receptor activity and impaired IRS phosphorylation weaken this signaling cascade, resulting in decreased GLUT4 translocation and diminished glucose uptake [48, 83]
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