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In this study, the difference in body weight reduction between tirzepatide- and semaglutide-treated groups can only partly explain the improvement in insulin sensitivity, lending support to the observation that tirzepatide was associated with improvements in insulin sensitivity associated with both body weight-lowering and a potential insulin-sensitizing effects of GIP

Previous research has shown that people with obesity often perceive tastes less intensely, and they have an inherently elevated desire for sweet and energy-dense food, Mojca Jensterle Sever, Ph.D., study author, said in a press release

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