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The Fras 2021 SURPASS-2 head-to-head trial against semaglutide demonstrated larger HbA1c and weight reductions for tirzepatide at all dose tiers, an outcome researchers attribute to the additional GIP-receptor arm contribution (PMID 32730231, PMID 34170647)
10.1097/00000658-200008000-00008 2 AltayC.CetinM.DogramaciI
**Enhanced Quality of Life:** * **Beyond the Scale:** Benefits often include increased energy levels, improved mobility, reduced joint pain, better sleep (especially if OSA improves), and increased confidence
As far as recent research results are concerned, the use of small-molecule drugs includes the treatment of kidney diseases, such as AKI, CKD, and RCC
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