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Benefits of B12 supplementation have been shown in a number of conditions, including diabetic neuropathy, back pain, mouth ulcers, autism spectrum disorder and elevated homocysteine levels, and it is generally considered to be very safe even at high dosages
Mood Changes : There have been anecdotal reports of mood swings or changes in emotional well-being, likely due to the changes in energy metabolism
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A study from 2006 didnt find any difference in effectiveness between sublingual and oral vitamin B12 supplements (Yazaki, 2006)
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