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Growth Hormone & IGF Research, 11(5), 266-272
Previous studies reported that the administration of the GLP-1R agonist exendin-4 (25 nmol/kg, twice daily) inhibits learning and memory formation through the suppression of synaptic plasticity in the hippocampus of a high fat diet mouse model (Gault et al., 2010
Pharm J
Nesse sentido, a depleo de carnitina no sangue, nos tecidos perifricos e nas clulas mononucleares poderia ser um fator agravante dos distrbios no metabolismo lipdico e das irregularidades na produo de citocinas (principal fator na progresso dos prejuzos das funes imunolgicas), freqentemente observados nos pacientes em uso de terapia anti-retroviral 6,8
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