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Semaglutide lowered the risk of major heart problems in people who already had heart disease or were at high risk
Eric Xu ORCID: orcid.org/0000-0002-6829-8144 1 Cell Research volume 30 , pages 11401142 (2020) Cite this article 10k Accesses 53 Citations 21 Altmetric Metrics details Dear Editor, The glucagon-like peptide-1 receptor (GLP-1R) belongs to class B G protein-coupled receptors (GPCRs)
More than a decade ago a study showed that GPR40 mediates the long-term FFA-induced lipotoxicity seen in the diabetic islets (254)
However, another study noted sex- differences, which could be related to sex steroid levels, in the response to GLP-1 agonists (246)
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