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Beyond bone health, the effects of GLP-1Ra on musculoskeletal health remain to be elucidated [82]

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Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver

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The 4-fluoro and 1-methyl substituents were optimized to balance metabolic stability (resistance to CYP-mediated oxidation) with receptor affinity

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