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Richie at Penn State University

Currently, no clinically significant changes in the absorption or action of co-administered oral medications have been reported, but patients with impaired kidney function taking medications that require weight-based dosing warrant more frequent monitoring

Body composition analysis using a time-domain NMR analyzer revealed that both doses of MOTS-c significantly retarded fat gain and that the high dose significantly increased lean mass in young mice (CD-1

As these drugs gain wider use, robust modeling studies will be essential to inform policy decisions, reimbursement frameworks, and clinical guidelines