Still, we dont have the big, long-term studies like we do for GLP-1 drugs, says Dr
Alongside liraglutide, semaglutide has been shown to effectively improve motor impairments, rescue tyrosine hydroxylase (TH) levels, reduce -synuclein accumulation, chronic inflammation response in the brain and lipid peroxidation, inhibit mitochondrial mitophagy signaling and protect dopaminergic neurons in the substantia nigra and striatum in MPTP mouse models of PD [81]
Lack of research is a problem here too, Al-Aly emphasized: The best evidence of this hypothetical effect is a preprint study that found that mice sought out their exercise wheel less after being injected with semaglutide
Sin embargo, "es crucial continuar con los tratamientos para mantener el peso, de lo contrario, es casi seguro que el paciente recuperar el peso perdido", advierte