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These transmembrane enzymes utilize NADPH to reduce O 2 , directly producing H 2 O 2 (as by NOX4, DUOX1/2) [72] or indirectly via O 2 generation (by NOX1-3) [73], which rapidly dismutates to H 2 O 2
Any change in hormone levels might reduce how well the pill works
No randomised controlled trials have investigated GLP-1 receptor agonists specifically for ADHD treatment
Nevertheless, the convergence of structural optimization, complementary mechanisms, documented synergy principles, and preserved hormonal selectivity makes this combination a scientifically compelling subject for continued investigation in appropriate research contexts
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