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In the ESC-treated group, the lesion-to-normal (L/N) uptake ratio peaked at 1-week post-transplantation and was significantly higher than the iPSC and non-grafted groups
[1] [7] These combined actions reduce abnormal electrical activity in the brain, which underlies its efficacy in epilepsy and migraine prevention
This mechanism may provide pain relief without the tolerance and dependence issues associated with direct opioid receptor agonists
Oxid Med Cell Longev 2019:5080843
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