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Semaglutide only targets GLP-1, limiting its pathway activation

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Methods: A PRISMA-guided systematic review was conducted using PubMed and MEDLINE databases with search terms glutathione AND topical AND skin OR dermatology. From 446 articles, only clinical trials on topical glutathione were included, excluding reviews, animal studies, and research on oral or intravenous glutathione

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications that mimic the action of naturally occurring GLP-1, a hormone produced in the intestines in response to food intake