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Therefore, patients also receiving an insulin secretagogue (e.g., sulfonylurea, meglitinide) may require a lower dose of the insulin secretagogue to reduce the risk of hypoglycemia [see Dosage and Administration]

Reinitiation Criteria: Clinicians should consider increasing the dose or reinitiating therapy if a patient experiences more than 5% weight regain

None of them work the same way

This Centers for Disease Control and Prevention (CDC)recognized lifestyle-change program has decreased the risk of developing type 2 diabetes by 58%, or even more in people over 60