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But know that dose modification is a legitimate tool for managing side effects, and a good provider will work with you to find the balance between therapeutic benefit and tolerability

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Reassuring clinical data are starting to accrue: two multinational population-based cohort studies found no increased risk of major congenital malformations, live births, pregnancy losses, and pregnancy terminations during the periconceptional period with GLP-1 RAs [139]

In BC, 5-FU combined with QUE further promoted the apoptosis of MCF-7 cells by increasing the expression of Bax, Caspase-9, and p53 genes and decreasing the expression of bcl-2 genes, indicating that QUE could enhance the sensitivity of 5-FU to BC (39)