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Frequency-dependent oscillatory shear testing demonstrated that both formulations exhibited predominantly solid-like viscoelastic behavior, with storage modulus ( G ) exceeding loss modulus ( G ) over all observed frequencies, and tan( ) values between 0.1 and 0.5 across the entire frequency range, indicative of robust physical cross-linking and structural integrity essential for depot formation ( Figure 2B , E )

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Nat Rev Neurosci (2015) 16(6):34557