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CCK-8 (orange, 2 g/kg body weight) or vehicle (black) injection on cumulative ad libitum food intake in 12- to 18-week-old male WT ( G ) and Bbs5 / ( H ) mice over 24 hours ( n = 79 per group)

Glucagon activation increases energy expenditure: your body burns more calories at rest through a process called thermogenesis

This hormone plays a key role in managing blood sugar and appetite by: Slowing digestion Reducing hunger signals Helping regulate glucose levels When GLP-1 agonists are used consistently, they can help reduce appetite, improve portion control, and support steady weight loss