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Listen and download: | American Society of Health-System Pharmacists

If the chronic cerebral hypoperfusion hypothesis is correct then brain neuronal accumulations of A1-42 and tau proteins must be considered downstream consequences rather than causes of AD [48]

In a db/db mouse model of type 2 diabetes, dapagliflozin treatment for 12 weeks inhibited the expression of TGF- , MCP-1, osteopontin and ICAM-1, and thereby inhibited diabetes-induced inflammation in the kidneys (154)