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Participants were randomized to increasing doses of once-weekly semaglutide or placebo
however, they should be reserved for inadequate weight loss despite implementing lifestyle interventions, according to the American Association of Clinical Endocrinologists (AACE) and American College of Endocrinology (ACE) 2016 clinical practice guideline
doi:10.2147/dddt.S484531 23
If you have read my other posts, you will know that hardly anyone who successfully manages to loose weight is actually able to keep it off, and the vast majority regain everything with a surplus
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