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Developed through systematic structure-activity relationship studies, it was engineered to optimize GH-releasing potency while minimizing effects on cortisol and prolactin secretion, a selectivity profile that distinguishes it from earlier, less refined GHRPs such as GHRP-2 and GHRP-6

doi: 10.2147/NDT.S101925 82 HillA

Retatrutide , a triple-action peptide (GIP/GLP-1/glucagon receptor agonist), is in late-stage clinical trials and has shown even more dramatic weight loss results than tirzepatide

Although their aesthetic use is sometimes mentioned, scientific evidence is still insufficient to confirm a direct effect on cellulite reduction or on improving skin firmness