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Although some of the metabolic benefits conferred by bariatric surgeries have been ascribed to changes in the secretory profiles of various gut hormones, the therapeutic potential of the enteroendocrine system as a viable target against metabolic diseases remain largely underexploited, except for incretin-mimetics

The beginning of 2026 brought one of the biggest changes to the GLP-1 medication landscape as a new medication for weight loss was approved, called orforglipron

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The medication works by affecting the areas of the brain responsible for hunger, leading to a noticeable reduction in appetite and food cravings