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Disturbed genomic integrity induces oxidative genetic damage, DNA oxidation, the activation of proto-oncogenes, and the inactivation tumour suppressor genes leading to proliferative effects and mutagenesis (113, 114)
S., Klau, J
Although studies have confirmed that GLP-1RAs do have a certain regulatory effect on the proliferation and apoptosis of tumor cells, the application of GLP-1RAs in tumor-related diseases is not currently its main indication, but GLP-1RAs can have a protective effect on the heart, kidney and other organs through their anti-inflammatory, antihypertensive, and lipid-regulating effects
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