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12R-LOX and eLOX-3 are engaged in the synthesis of the cornified envelope (CE) through the enzymatic synthesis of lipid oxide products in the epidermis to maintain the skin barrier and reduce transepidermal water loss (TEWL) (Krieg and Furstenberger, 2014)
Vitamin B12 is a foundational nutrient essential for maintaining an active, balanced lifestyle, yet it is easily depleted by modern stressors and is notably absent from plant-based diets
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In the second step, -Glu-Cys and Gly form GSH via GSS activity (Stockwell et al., 2017)
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