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Normal BMI was not a barrier to prescribing oral semaglutide, as normal-weight patients were also treated, as previously suggested ( The reduced oral bioavailability (0.4-1%) and complex pharmacokinetics of oral semaglutide make appropriate counseling and patient adherence to the administration instructions crucial, and are potential obstacles to the success of this treatment regimen

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J Antibiot (Tokyo) 1993

"One key misunderstanding is that [obesity] is a disease of willpower, when in fact there is underlying biology that prevents people from losing weight and keeping it off," Novo Nordisk stated in a news release