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Its concurrent engagement of GLP-1R, GIPR, and GCGR distinguishes it structurally and pharmacologically from both selective GLP-1R agonists such as semaglutide and dual GLP-1R/GIPR agonists such as tirzepatide
So I think many of us would be hopeful that we will see a clear benefit there
It is linked to Mitsubishi Corporation Life Sciences
Its not 100% clear that the drugs are associated [with NAION], says Amanda Henderson, MD, chief of the Neuro-ophthalmology Division at the Wilmer Eye Institute and associate professor of medicine at Johns Hopkins School of Medicine
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