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14 : 107115 De Falco FA, D'Angelo E, Grimaldi G, Scafuro F, Sachez F, Caruso G
The molecule is classified as a triple receptor agonist because it interacts with three endocrine receptors involved in metabolic regulation: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)
Insulin is the antagonist of growth hormone
A study published in The Journal of Clinical Investigation demonstrated that glucagon infusion increases energy expenditure by 100200 calories per day in humans (Nair, 1987) Enhanced hepatic fat oxidation Glucagon stimulates the liver to break down stored fat (lipids) and convert them into energy through a process called beta-oxidation
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