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However, liraglutide has been available since 2010, providing over 15 years of real-world use across millions of patients without confirmed increased MTC signal in humans
20 Similar results were obtained in a phase III trial including saxagliptin 5 mg and 10 mg in combination with maximal doses of metformin compared to saxagliptin and metformin alone
Edward Walker, Senior Scientist at the New Zealand Institute for Bioeconomy Science
Gastrointestinal side effects Nausea is dose-dependent, ranging from approximately 14% at 1 mg to 60% at 12 mg, mostly during titration
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