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In the words of Gustavo Bounous, MD, retired professor of surgery at McGill University in Montreal, Its the [bodys] most important antioxidant because its within the cell. Although its absolutely essential to maintaining a healthy immune system, it is not technically an essential nutrient because the body can create it from the amino acids L-cysteine, L-glutamic acid (a component of glutamine) and glycine

Hence, the GSH/GSSG ratio represents a marker of oxidative stress

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