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"All these new formulations are coming out," said Brian Roe, an Ohio State professor of food, agricultural and environmental sciences who led the GLP-1 study
Doses above 3,000 mg/day may cause GI side effects: nausea, diarrhea, abdominal cramps, and a fishy body odor (from trimethylamine production by gut bacteria) If you have kidney disease: L-carnitine clearance is renally dependent
Ten months earlier, the Phase 3 Exenatide-PD3 trial had reached the same conclusion in Parkinsons disease: no effect on progression across 194 patients followed for 96 weeks, with no treatment difference on dopamine-transporter imaging in the trials imaging substudy [2]
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