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Although many transporter-utilizing (pro)drugs and nanocarriers have been developed to improve the uptake of drugs to the brain, their success rate of translation from preclinical development to humans is negligible

Designed exclusively for Research Use Only (RUO) , the Alluvi Research Pen arrives in a ready-to-use format that eliminates manual reconstitution, helping researchers maintain consistent handling procedures across controlled laboratory studies

However, the secondary endpoint of change in scores for clinical and cognitive measures and the exploratory endpoint of brain volume showed statistically significant benefit

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