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BPC-157 in a rat medial collateral ligament model

FDA staff had recommended against including emideltide, which is used for insomnia and opioid withdrawal, on the list in part because studies on its efficacy are limited and because there are alternative therapies available to treat those conditions

Both have overlapping roles, but overexpression studies made clear that KRPs inhibit both M- and S phase entries, while SMRs are assumed to merely negatively affect mitosis (Kumar and Larkin 2017)