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Endogenous MOTS-c levels also decline with age, which helps explain why metabolic efficiency tends to drop in our 40s and 50s regardless of diet or exercise
Marso SP, et al: Semaglutide and cardiovascular outcomes in patients with type 2 diabetes
Semaglutide 2.4 mg (Wegovy) is approved under NICE technology appraisal TA875, and tirzepatide (Mounjaro) has also received a NICE technology appraisal for weight management
Based on self-reported data from 518 Nexlife members, the average weight loss in the first six months is 29 lbs when combining GLP-1 injections with diet and exercise
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