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Quantification of times of B-fission events within 10 min per cell in ctrl, ATG7 KO, shTFEB and ATG7 KO+shTFEB HeLa cells (p, n = 45, three experiments)
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Chronic neuroinflammationmediated by activated microglia and astrocytesexacerbates neuronal injury through the release of pro-inflammatory cytokines such as TNF- and IL-1 (Singh et al., 2019)
So, it is relevant to question whether APAP treatment could decrease Cys availability necessary to sustain protein reserves, notably in skeletal muscle, and consequently worsen sarcopenia and frailty in older adults
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