Combining antiangiogenic agents, such as saikosaponin b2 which targets the VEGF/ERK/HIF-1 pathway, with immunotherapy enhances treatment efficacy
Numerous reports also emphasize the neuroprotective role of GLP-1 mediated signaling, as it was proven to protect synapses, improve synaptic functions, enhance neurogenesis, protect neurons from oxidative stress, and reduce neuronal apoptosis
However, there are also cases when additional factors such as lack of sleep, poor diet, and deficiency of other vitamins like iron, folate, and others, contribute to the issue
Zepbounds commercial rise showed that dual agonism could become the next dominant mechanism in obesity care