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Because no studies have evaluated potential risks, such as effects on the fetus or pregnancy outcomes, clinicians advise against NAD+ therapy during pregnancy out of an abundance of caution

Important factors for the loading phase include: Severity of initial deficiency Presence of neurological symptoms Patients overall health status Response to initial doses as assessed through follow-up laboratory tests By following this guideline, doctors can quickly restore vitamin B12 levels

Repeat twice per week for maximum benefits This program may include compounded medications that are clinical substitutions of brand name medications compounded by licensed compounding pharmacies under section 503A

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