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Transgenic mice in which GCLC expression is abolished in hepatocytes have 58% of normal hepatic GSH levels and manifest liver pathologies characteristic of the various clinical stages of fatty liver disease 8,9
Biochim Biophys Acta 1830:32893303
They are promising and widely discussed, but they are not simple mainstream answers
Insulin-like growth factor-I receptor (IGF-IR) translocates to nucleus and autoregulates IGF-IR gene expression in breast cancer cells
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