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In particular, hemocompatibility of blood-contacting devices is tested in vitro in accordance with the ISO standard 10993-4 guidelines, and this testing comprises evaluation of thrombosis, the blood coagulation system, the complement system, and multiple effects on platelets and leukocytes [464]
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In animal models of atherosclerosis, the GLP1 analogue exendin 4 substantially reduced the accumulation of monocytes and macrophages in the vascular wall and inhibited atherogenesis by regulating inflammation in macrophages 95
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