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Ipamorelin: Stimulates GH release via the ghrelin receptor pathway (GHS-R) (Raun et al., 1998)
Power calculations suggest that previous studies would have had limited power to detect an effect size similar to that identified in our study (Supplementary Table 23), and also differed in terms of drug type, disease cohort and analytical choices
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The mechanism involves improved insulin sensitivity, normalized leptin signaling, and restoration of the luteinizing hormone (LH) pulse necessary for regular ovulation
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