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Allen NE, Travis RC, Appleby PN, Albanes D, Barnett MJ, Black A, et al

66,67 In addition, ferroptotic cancer cells secrete extracellular factors, including LGALS13, that modulate the antioxidant state of adjacent cells, thereby priming them for subsequent ferroptotic collapse

In addition, the thiolester may directly combat the ability of fentanyl to suppress the central processes driving expiration under fentanyl-induced hypoxic/hypercapnic conditions and/or the direct inhibitory effects of fentanyl on expiratory muscle activity 11,12,13,14,15 , although it should be noted that there is evidence that opioids can actually increase expiratory muscle activity under certain circumstances 135

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