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Adding targeted training helps too

In a head-to-head trial against semaglutide (the SURPASS-2 trial), tirzepatide produced significantly greater weight loss, with participants taking the highest dose of tirzepatide losing an average of 11.2 kg (24.7 lbs), compared to 5.7 kg (12.5 lbs) for those taking semaglutide 1 mg

In traditional settings, peptides like GLP-1 and GIP were administered through subcutaneous injections - a method that, while effective, introduced challenges around storage, sterility, and user compliance in longer-term studies