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Even with the best enhancement strategies currently available, nasal bioavailability for peptides in this molecular weight range typically reaches 15-45% in optimized animal models, with human bioavailability often lower
It is suitable for intramuscular and subcutaneous drug preparation, but not for intravenous injection itself
This practice serves multiple purposes
Ohrstrom CC, Worm D, Kielgast UL, Holst JJ, Hansen DL (2020) Evidence for relationship between early dumping and postprandial hypoglycemia after Roux-en-Y gastric bypass
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