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Huang R, Ji F, Jiang Y, Li S, Su M, Zhong Y, et al

Changes in DNA methylation and gene expression of insulin and obesity-related gene PIK3R1 after Roux-en-Y gastric bypass

Some participants discontinued treatment due to side effects, particularly at higher doses, a reminder that individual tolerance and clinical monitoring are important considerations in any metabolic intervention

Over a trial period of 31 days, participants treated with Y14 peptide experienced a weight reduction of 2.9 to 3.6 kilograms, with a 38% to 55% reduction in food intake compared to the placebo group