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J Diabetes (2015) 7(4):5848.10.1111/1753-0407.12282 28 SunHXLuNLiuDMZhaoLSunLHZhaoHYet alThe bone-preserving effects of exendin-4 in ovariectomized rats

Its used on demand rather than daily, so cumulative exposure is limited compared with maintenance medications

Beyond sleep, combined estrogen and progesterone therapy has been linked to improvements in insulin sensitivity and lipid profiles in women during early menopause [22], adding a further layer of metabolic benefit to the combination