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This tool is optimized for tissues with closely related cell types, employing a probabilistic model along with weighted nonnegative least squares regression to estimate the relative abundance of pigment cell types from bulk transcriptomic data 64
Xue et al., 2004
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The proglucagon gene encodes a 180-amino acid precursor that, depending on the tissue-specific expression of processing enzymes, yields different active peptides: in the pancreatic alpha cells, PCSK2 processing produces glucagon
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