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Transcriptome analysis of hepsin / and wild-type mice during the early period after APAP exposure To clarify the function of hepsin in the early stages of APAP-induced hepatotoxicity, a transcriptome analysis employing RNA sequencing was conducted within the first 2 h post-APAP administration

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A note on the mixing itself (not just the math) The arithmetic assumes a clean reconstitution

Histological evidence of toxicity includes fatty change and hepatocellular degeneration and necrosis (Figure 8)