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Potential Synergies Complementary Actions: Since GLP-1 focuses on metabolism while GLP-2 targets gut health, they dont compete for the same receptors or mechanisms
Retatrutide is taken once weekly by subcutaneous injection, with doses escalated stepwise from a low starting dose
The program pairs GLP-1 medications with behavioral coaching, and it is not cheap
For Hashimoto's patients, this discontinuation requires careful planning because: Thyroid hormone requirements increase significantly during pregnancy (typically 25-50% higher) Weight regain after GLP-1 discontinuation will change levothyroxine requirements again Optimal thyroid function before conception is critical for fetal brain development If you discover you are pregnant while on a GLP-1 medication , stop the medication immediately and contact your healthcare provider for urgent thyroid function testing and levothyroxine dose adjustment
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