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In addition, regulatory and quality personnel are needed

Recent investigations have focused more on combination therapies, particularly pairing glutathione with its precursors (l-cystine, cysteine peptides) or other antioxidants (vitamin C, alpha-lipoic acid, zinc), reflecting the understanding that synergistic effects may enhance skin-lightening outcomes

Higgins JP, Altman DG, Gtzsche PC, et al

Although these experiments had no effects on tumor viability, the concept was later picked up by Wilhelm Brnings 178 , 179 who combined maximally tolerable doses of insulin treatment with a KD into a de-glycation method (Entzuckerungsmethode) for the treatment of head and neck cancer patients in his clinic