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The rationale is that pulsatile GH release may have different tissue effects than continuous elevation, though this has not been proven in comparative studies
PMID: 5938029 Gupta S, Gupta N
Individuals who choose to take glutathione long term should follow recommended dosages and maintain regular medical guidance if needed
Other side effects Additional reported side effects include: Joint pain and water retention Muscle and joint aches Headaches and nausea Receptor desensitization with prolonged use Potential suppression of natural GH and IGF-1 production Who should avoid IGF-1 LR3 Certain groups should not use IGF-1 LR3: Anyone with active cancer or tumor history Those with severe insulin resistance or diabetes Pregnant or nursing women Anyone under 25 whose growth plates haven't closed Those with existing hormonal imbalances IGF-1 LR3 is not FDA-approved for general medical use and remains primarily a research compound
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